News | Clinical Bioinformatics Area

El Área de Bioinformática Clínica de la sanidad andaluza presenta sus líneas de investigación en medicina personaliza
Submitted by jdopazo on Sun, 11/18/2018 - 19:02

Esta área, que trabaja en el denominado "big data genómico", ha presentado sus avances en dos encuentros en Sevilla y Granada

El Área de Investigación en Bioinformática de la sanidad pública andaluza ha presentado sus líneas de investigación y sus futuros proyectos las Jornadas Salud Investiga en Granada y en el congreso del sector biotecnológico Biospain 2018 en Sevilla.
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Big data y medicina personalizada: datos que curan
Submitted by jdopazo on Mon, 11/05/2018 - 17:00

En la actualidad existen más datos e información que nunca y aparatos capaces de generar enórmes volúmenes de datos biomédicos, incluyendo datos genómicos, a un coste realmente asequible. Todo este big data clínico abre la puerta al descubrimiento de nuevos tratamientos más precisos, nuevas formas de diagnóstico mas exactas y, en general, a toda una serie de avances encuadrados de forma general dentro de la medicina personalizada y de precisión.
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LRH-1 agonism favours an immune-islet dialogue which protects against diabetes mellitus.
Submitted by jdopazo on Fri, 11/02/2018 - 11:37
Cobo-Vuilleumier N, Lorenzo PI, Rodríguez NGarcía, et al. LRH-1 agonism favours an immune-islet dialogue which protects against diabetes mellitus. Nat Commun. 2018;9(1):1488. doi:10.1038/s41467-018-03943-0.
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Evolution of the Quorum network and the mobilome (plasmids and bacteriophages) in clinical strains of Acinetobacter baumannii during a decade.
Submitted by jdopazo on Fri, 11/02/2018 - 11:36
López M, Rueda A, Florido JP, et al. Evolution of the Quorum network and the mobilome (plasmids and bacteriophages) in clinical strains of Acinetobacter baumannii during a decade. Sci Rep. 2018;8(1):2523. doi:10.1038/s41598-018-20847-7.
A crowdsourced analysis to identify ab initio molecular signatures predictive of susceptibility to viral infection.
Submitted by jdopazo on Fri, 11/02/2018 - 11:33
Fourati S, Talla A, Mahmoudian M, et al. A crowdsourced analysis to identify ab initio molecular signatures predictive of susceptibility to viral infection. Nat Commun. 2018;9(1):4418. doi:10.1038/s41467-018-06735-8.
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The modular network structure of the mutational landscape of Acute Myeloid Leukemia.
Submitted by jdopazo on Fri, 11/02/2018 - 11:33
Ibáñez M, Carbonell-Caballero J, Such E, et al. The modular network structure of the mutational landscape of Acute Myeloid Leukemia. PLoS One. 2018;13(10):e0202926. doi:10.1371/journal.pone.0202926.
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The first complete genomic structure of Butyrivibrio fibrisolvens and its chromid.
Submitted by jdopazo on Fri, 11/02/2018 - 11:32
Hernáez JRodríguez, Cucchi MEsperanza, Cravero S, et al. The first complete genomic structure of Butyrivibrio fibrisolvens and its chromid. Microb Genom. 2018;4(10). doi:10.1099/mgen.0.000216.
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Gene expression integration into pathway modules reveals a pan-cancer metabolic landscape.
Submitted by jdopazo on Fri, 11/02/2018 - 11:31
Cubuk C, Hidalgo MR, Amadoz A, et al. Gene expression integration into pathway modules reveals a pan-cancer metabolic landscape. Cancer Res. 2018. doi:10.1158/0008-5472.CAN-17-2705.
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Models of cell signaling uncover molecular mechanisms of high-risk neuroblastoma and predict disease outcome.
Submitted by jdopazo on Fri, 11/02/2018 - 11:02
Hidalgo MR, Amadoz A, Cubuk C, Carbonell-Caballero J, Dopazo J. Models of cell signaling uncover molecular mechanisms of high-risk neuroblastoma and predict disease outcome. Biol Direct. 2018;13(1):16. doi:10.1186/s13062-018-0219-4.
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A comparison of mechanistic signaling pathway activity analysis methods.
Submitted by jdopazo on Fri, 11/02/2018 - 11:01
Amadoz A, Hidalgo MR, Cubuk C, Carbonell-Caballero J, Dopazo J. A comparison of mechanistic signaling pathway activity analysis methods. Brief Bioinform. 2018. doi:10.1093/bib/bby040.
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