SARS-CoV-2

Aripiprazole as protector against COVID-19 mortality.

Submitted by jdopazo on Fri, 10/11/2024 - 17:07

Loucera-Muñecas C, Canal-Rivero M, Ruiz-Veguilla M, et al. Aripiprazole as protector against COVID-19 mortality. Sci Rep. 2024;14(1):12362. doi:10.1038/s41598-024-60297-y.

Drug-target identification in COVID-19 disease mechanisms using computational systems biology approaches.

Submitted by jdopazo on Mon, 03/11/2024 - 20:26

Niarakis A, Ostaszewski M, Mazein A, et al. Drug-target identification in COVID-19 disease mechanisms using computational systems biology approaches. Front Immunol. 2024;14:1282859. doi:10.3389/fimmu.2023.1282859.

Evaluation of a combined detection of SARS-CoV-2 and its variants using real-time allele-specific PCR strategy: an advantage for clinical practice.

Submitted by jdopazo on Thu, 01/04/2024 - 12:13

Chaves-Blanco L, de Salazar A, Fuentes A, et al. Evaluation of a combined detection of SARS-CoV-2 and its variants using real-time allele-specific PCR strategy: an advantage for clinical practice. Epidemiol Infect. 2023;151:e201. doi:10.1017/S095026882300184X.

Assessing the Impact of SARS-CoV-2 Lineages and Mutations on Patient Survival.

Submitted by jdopazo on Wed, 09/28/2022 - 10:33

Loucera C, Perez-Florido J, Casimiro-Soriguer CS, et al. Assessing the Impact of SARS-CoV-2 Lineages and Mutations on Patient Survival. Viruses. 2022;14(9). doi:10.3390/v14091893.

Highly accurate whole-genome imputation of SARS-CoV-2 from partial or low-quality sequences.

Submitted by rgarcia on Wed, 12/15/2021 - 09:47

Ortuno FM, Loucera C, Casimiro-Soriguer CS, et al. Highly accurate whole-genome imputation of SARS-CoV-2 from partial or low-quality sequences. Gigascience. 2021;10(12). doi:10.1093/gigascience/giab078.

COVID19 Disease Map, a computational knowledge repository of virus-host interaction mechanisms.

Submitted by jdopazo on Wed, 10/20/2021 - 09:53

Ostaszewski M, Niarakis A, Mazein A, et al. COVID19 Disease Map, a computational knowledge repository of virus-host interaction mechanisms. Mol Syst Biol. 2021;17(10):e10387. doi:10.15252/msb.202110387.

Drug repurposing for COVID-19 using machine learning and mechanistic models of signal transduction circuits related to SARS-CoV-2 infection.

Submitted by jdopazo on Fri, 02/12/2021 - 18:29

Loucera C, Esteban-Medina M, Rian K, Falco MM, Dopazo J, Peña-Chilet M. Drug repurposing for COVID-19 using machine learning and mechanistic models of signal transduction circuits related to SARS-CoV-2 infection. Signal Transduct Target Ther. 2020;5(1):290. doi:10.1038/s41392-020-00417-y.

COVID-19 Disease Map, building a computational repository of SARS-CoV-2 virus-host interaction mechanisms.

Submitted by jdopazo on Mon, 05/18/2020 - 13:41

Ostaszewski M, Mazein A, Gillespie ME, et al. COVID-19 Disease Map, building a computational repository of SARS-CoV-2 virus-host interaction mechanisms. Sci Data. 2020;7(1):136. doi:10.1038/s41597-020-0477-8.