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Signal Transduction

Large-scale transcriptional profiling and functional assays reveal important roles for Rho-GTPase signalling and SCL during haematopoietic differentiation of human embryonic stem cells.

Submitted by iguillen on Tue, 06/18/2019 - 11:24
Yung S, Ledran M, Moreno-Gimeno I, et al. Large-scale transcriptional profiling and functional assays reveal important roles for Rho-GTPase signalling and SCL during haematopoietic differentiation of human embryonic stem cells. Hum Mol Genet. 2011;20(24):4932-46. doi:10.1093/hmg/ddr431.

Early transcriptional defense responses in Arabidopsis cell suspension culture under high-light conditions.

Submitted by iguillen on Tue, 06/18/2019 - 11:22
González-Pérez S, Gutiérrez J, Garcia-Garcia F, et al. Early transcriptional defense responses in Arabidopsis cell suspension culture under high-light conditions. Plant Physiol. 2011;156(3):1439-56. doi:10.1104/pp.111.177766.

Early peroxisome proliferator-activated receptor gamma regulated genes involved in expansion of pancreatic beta cell mass.

Submitted by iguillen on Tue, 06/18/2019 - 11:22
Vivas Y, Martinez-Garcia C, Izquierdo A, et al. Early peroxisome proliferator-activated receptor gamma regulated genes involved in expansion of pancreatic beta cell mass. BMC Med Genomics. 2011;4:86. doi:10.1186/1755-8794-4-86.

IL1β induces mesenchymal stem cells migration and leucocyte chemotaxis through NF-κB.

Submitted by iguillen on Tue, 06/18/2019 - 10:41
Carrero R, Cerrada I, Lledó E, et al. IL1β induces mesenchymal stem cells migration and leucocyte chemotaxis through NF-κB. Stem Cell Rev Rep. 2012;8(3):905-16. doi:10.1007/s12015-012-9364-9.

Inferring the functional effect of gene expression changes in signaling pathways.

Submitted by iguillen on Tue, 06/18/2019 - 10:12
Sebastián-Leon P, Carbonell J, Salavert F, Sánchez R, Medina I, Dopazo J. Inferring the functional effect of gene expression changes in signaling pathways. Nucleic Acids Res. 2013;41(Web Server issue):W213-7. doi:10.1093/nar/gkt451.

Sequencing and functional analysis of the genome of a nematode egg-parasitic fungus, Pochonia chlamydosporia.

Submitted by iguillen on Mon, 06/17/2019 - 12:33
Larriba E, Jaime MDLA, Carbonell-Caballero J, et al. Sequencing and functional analysis of the genome of a nematode egg-parasitic fungus, Pochonia chlamydosporia. Fungal Genet Biol. 2014;65:69-80. doi:10.1016/j.fgb.2014.02.002.

Using activation status of signaling pathways as mechanism-based biomarkers to predict drug sensitivity.

Submitted by iguillen on Mon, 06/17/2019 - 12:21
Amadoz A, Sebastián-Leon P, Vidal E, Salavert F, Dopazo J. Using activation status of signaling pathways as mechanism-based biomarkers to predict drug sensitivity. Sci Rep. 2015;5:18494. doi:10.1038/srep18494.

Deregulation of key signaling pathways involved in oocyte maturation in FMR1 premutation carriers with Fragile X-associated primary ovarian insufficiency.

Submitted by iguillen on Tue, 06/11/2019 - 10:22
Alvarez-Mora MI, Rodriguez-Revenga L, Madrigal I, et al. Deregulation of key signaling pathways involved in oocyte maturation in FMR1 premutation carriers with Fragile X-associated primary ovarian insufficiency. Gene. 2015;571(1):52-7. doi:10.1016/j.gene.2015.06.039.

High throughput estimation of functional cell activities reveals disease mechanisms and predicts relevant clinical outcomes.

Submitted by iguillen on Mon, 06/10/2019 - 12:01
Hidalgo MR, Cubuk C, Amadoz A, Salavert F, Carbonell-Caballero J, Dopazo J. High throughput estimation of functional cell activities reveals disease mechanisms and predicts relevant clinical outcomes. Oncotarget. 2017;8(3):5160-5178. doi:10.18632/oncotarget.14107.