Protein Interaction Mapping

COVID19 Disease Map, a computational knowledge repository of virus-host interaction mechanisms.

Submitted by jdopazo on Wed, 10/20/2021 - 09:53

Ostaszewski M, Niarakis A, Mazein A, et al. COVID19 Disease Map, a computational knowledge repository of virus-host interaction mechanisms. Mol Syst Biol. 2021;17(10):e10387. doi:10.15252/msb.202110387.

Taxonomic variations in the gut microbiome of gout patients with and without tophi might have a functional impact on urate metabolism.

Submitted by jdopazo on Mon, 05/31/2021 - 09:28

Méndez-Salazar EOrlando, Vázquez-Mellado J, Casimiro-Soriguer CS, et al. Taxonomic variations in the gut microbiome of gout patients with and without tophi might have a functional impact on urate metabolism. Mol Med. 2021;27(1):50. doi:10.1186/s10020-021-00311-5.

Evidence for systems-level molecular mechanisms of tumorigenesis.

Submitted by iguillen on Thu, 07/04/2019 - 12:45

Hernández P, Huerta-Cepas J, Montaner D, et al. Evidence for systems-level molecular mechanisms of tumorigenesis. BMC Genomics. 2007;8:185. doi:10.1186/1471-2164-8-185.

SNOW, a web-based tool for the statistical analysis of protein-protein interaction networks.

Submitted by iguillen on Thu, 07/04/2019 - 11:44

Minguez P, Götz S, Montaner D, Al-Shahrour F, Dopazo J. SNOW, a web-based tool for the statistical analysis of protein-protein interaction networks. Nucleic Acids Res. 2009;37(Web Server issue):W109-14. doi:10.1093/nar/gkp402.

Discovering the hidden sub-network component in a ranked list of genes or proteins derived from genomic experiments.

Submitted by iguillen on Tue, 06/18/2019 - 10:35

García-Alonso L, Alonso R, Vidal E, et al. Discovering the hidden sub-network component in a ranked list of genes or proteins derived from genomic experiments. Nucleic Acids Res. 2012;40(20):e158. doi:10.1093/nar/gks699.

PTMcode v2: a resource for functional associations of post-translational modifications within and between proteins.

Submitted by iguillen on Tue, 06/11/2019 - 10:44

Minguez P, Letunic I, Parca L, et al. PTMcode v2: a resource for functional associations of post-translational modifications within and between proteins. Nucleic Acids Res. 2015;43(Database issue):D494-502. doi:10.1093/nar/gku1081.

A Pan-Cancer Catalogue of Cancer Driver Protein Interaction Interfaces.

Submitted by iguillen on Tue, 06/11/2019 - 10:23

Porta-Pardo E, García-Alonso L, Hrabe T, Dopazo J, Godzik A. A Pan-Cancer Catalogue of Cancer Driver Protein Interaction Interfaces. PLoS Comput Biol. 2015;11(10):e1004518. doi:10.1371/journal.pcbi.1004518.

Identification of the Photoreceptor Transcriptional Co-Repressor SAMD11 as Novel Cause of Autosomal Recessive Retinitis Pigmentosa.

Submitted by iguillen on Mon, 06/10/2019 - 12:08

Corton M, Avila-Fernández A, Campello L, et al. Identification of the Photoreceptor Transcriptional Co-Repressor SAMD11 as Novel Cause of Autosomal Recessive Retinitis Pigmentosa. Sci Rep. 2016;6:35370. doi:10.1038/srep35370.