@article {16566817,
	title = {Exploring the reasons for the large density of triplex-forming oligonucleotide target sequences in the human regulatory regions},
	journal = {BMC Genomics},
	volume = {7},
	year = {2006},
	note = {Goni, Josep Ramon Vaquerizas, Juan Manuel Dopazo, Joaquin Orozco, Modesto Research Support, Non-U.S. Gov{\textquoteright}t England BMC genomics BMC Genomics. 2006 Mar 27;7:63.},
	pages = {63},
	abstract = {BACKGROUND: DNA duplex sequences that can be targets for triplex formation are highly over-represented in the human genome, especially in regulatory regions. RESULTS: Here we studied using bioinformatics tools several properties of triplex target sequences in an attempt to determine those that make these sequences so special in the genome. CONCLUSION: Our results strongly suggest that the unique physical properties of these sequences make them particularly suitable as "separators" between protein-recognition sites in the promoter region.},
	keywords = {Animals Base Sequence Computational Biology DNA/chemistry/*genetics/*metabolism Genome, Genetic/genetics Regulatory Sequences, Human/genetics Humans Mice Nucleic Acid Conformation Nucleotides/genetics Oligonucleotides/chemistry/*genetics/*metabolism Promoter Regions, Nucleic Acid/*genetics Transcription Factors/metabolism},
	url = {http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve\&db=PubMed\&dopt=Citation\&list_uids=16566817},
	author = {Goni, J. R. and Vaquerizas, J. M. and Dopazo, J. and Orozco, M.}
}
